Butafenacil: A positive control for identifying anemia- and variegate porphyria-inducing chemicals
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چکیده
منابع مشابه
Butafenacil: A positive control for identifying anemia- and variegate porphyria-inducing chemicals
Butafenacil is an herbicide that inhibits protoporphyrinogen oxidase (PPOX), an enzyme that catalyzes oxidation of protoporphyrinogen IX to protoporphyrin IX during chlorophyll and heme biosynthesis. Based on a high-content screen, we previously identified butafenacil as a potent inducer of anemia in zebrafish embryos. Therefore, the objective of this study was to begin investigating the utilit...
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1 NIHR University College London Hospitals Biomedical Research Centre, Department of Clinical and Experimental Epilepsy, UCL Institute of Neurology, Queen Square, London WC1N 3BG, UK, and Epilepsy Society, Chalfont St Peter, SL9 0RJ, UK. 2 Neuroscience Department, Polytechnic University of Marche, Ancona 60100, Italy 3 Royal Victoria Infirmary, Newcastle-Upon Tyne, UK 4 Department of Laboratory...
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ژورنال
عنوان ژورنال: Toxicology Reports
سال: 2015
ISSN: 2214-7500
DOI: 10.1016/j.toxrep.2015.07.006